Endocrine Abstracts

Symptomatic hyperparathyroid patients are under risk of increased cardiovascular mortality, associated with left ventricular hypertrophy, diastolic dysfunction and accelerated atherosclerosis. Data on asymptomatic hyperparathyroid patients are conflicting. This study aimed to determine diastolic dysfunction and its association with carotis intima media thickness (CIMT) and flow-mediated vasodilation (FMD) in a group of asymptomatic hyperparathyroid patients.<p class="abste...

The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a disorder of impaired water excretion caused by inability to suppress secretion of antidiuretic hormone. The therapy of SIADH varies with severity of hyponatremia and presence or absence of symptoms. Non-peptide vasopressin receptor antagonists (vaptans) are effective at increasing sodium in euvolemic and hypervolemic states and appear safe. We aimed to evaluate the efficacy of tolvaptan in euvolemic h...

Aim: It is aimed to evaluate whether arterial stiffness, which is an independent risk indicator for hyperthyroid cardiovascular diseases, is affected by pulse wave analysis (PWA) and to observe changes in patients treated with hyperthyroidism.Methods: A total of 102 volunteers were included in the study (30 in the overt hyperthyroid group, 28 in the subclinical hyperthyroid group and 14 with euthyroidism by antithyroid therapy and 30 healthy). The arteri...

AimPheochromocytoma and paraganglioma are rare neuroendocrine tumors, that can be diagnosed incidentally or with symptoms that may be confused with other diseases. In our study, we aimed to demonstrate our clinical biochemical and pathological experiences with pheochromocytoma and paraganglioma cases.MethodThe clinical, biochemical, radiological, and pathological data of a total of 79 patients diagnosed with ...

PurposeInferior petrosal sinus sampling (IPSS) is the gold standard test for the differentiation of pituitary Cushing disease from the ectopic ACTH syndrome (EAS). The measurement of prolactin during IPSS can be helpful to improve the accuracy of the procedure. We aimed to evaluate the effect of measuring prolactin levels as a predictor for the accuracy of IPSS procedure and evaluate its’ impact on the lateralization of adenoma.<p class="abstext...

Introduction: Obesity is a component of eating disorders grouped under several eating disturbances due to emotional problems. Eating habits are directly influenced by eating disorders. Eating disorder rates in obese patients are reported to be 15-50% in various populations. This study aimed to evaluate obesity related eating habits (OREH) in obese patients who followed in an obesity center.Methods: A total of 752 (F/M: 636/116, 42.6&pm;11.6 yrs ) obese p...

A 45-year-old female patient with diagnosis of hypertension was admitted to Acibadem University Hospital for colonoscopy due to perianal abscess and rectovaginal fistula. She had been diagnosed with hypertension for 7 years and had been using 3 different classes of antihypertensive drugs. Intermittent hypertensive attacks and hospitalization for myocarditis history was documented. During anesthesia induction for colonoscopy her condition acutely worsened and she became hemodyn...

Introduction: Increasing evidence suggesting an integral role of vitamin D in skeletal muscle function. The relationship between muscle strength and vitamin D status has been investigated to some degree in older populations, however there has been very little research in younger adult women. This study aims to measure the effects of vitamin D on handgrip strength in young adult women.Method: A total of 141 healthy women with mean age of 33.8±6.8 wer...

Background and aim: As a prognostic marker, copeptin levels were independent predictors of survival in critically ill patients suffering from hemorrhagic and septic shock. Copeptin levels also have prognostic implications in chronic diseases other than acute illness. The stress-mediated activation of the HPA axis may be have role in the pathogenesis of the insulin resistance, metabolic syndrome, and diabetes. Furthermore, AVP action has been linked to liver glycogenolysis and ...

Generously supported by IPSEN)-->Acromegaly is a chronic disease with an important impact on patients, health-related quality of life (HRQoL). Acromegaly quality of life questionnaire (AcroQoL) is a disease-generated QoL questionnaire comprising 22 questions each having five possible responses scored 1–5, the maximum score of 110 reflecting best possible QOL, and quoted as a percentage. The 22 items break down into two categorie...